The Face Of Aids, Therese Frare, 1990

David Kirby died surrounded by his family. But Therese Frare’s photograph of the 32-year-old man on his deathbed did more than just capture the heartbreaking moment. It humanized AIDS, the disease that killed Kirby, at a time when it was ravaging victims largely out of public view. Frare’s photograph, published in LIFE in 1990, showed how the widely misunderstood disease devastated more than just its victims. It would be another year before the red ribbon became a symbol of compassion and resilience, and three years before President Bill Clinton created a White House Office of National AIDS Policy. In 1992 the clothing company Benetton used a colorized version of Frare’s photograph in a series of provocative ads. Many magazines refused to run it, and a range of groups called for a boycott. But Kirby’s family consented to its use, believing that the ad helped raise critical awareness about AIDS at a moment when the disease was still uncontrolled and sufferers were lobbying the federal government to speed the development of new drugs. “We just felt it was time that people saw the truth about AIDS,” Kirby’s mother Kay said. Thanks to Frare’s image, they did.